• 基因名称：
• TFPI

• 蛋白名称：
• Tissue factor pathway inhibitor

• Human Gene Id：
• 7035

• Human Swiss Prot No：
• P10646

• Mouse Swiss Prot No：
• O54819

• 特异性：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• 储存：
• 2-8°C/6 months

• 其他名称：
• TFPI;LACI;TFPI1;Tissue factor pathway inhibitor;TFPI;Extrinsic pathway inhibitor;EPI;Lipoprotein-associated coagulation inhibitor;LACI

• 检测方法：
• Colorimetric

• 背景：
• domain:This inhibitor contains three inhibitory domains. The first domain interacts with VIIa and TF, the second one with Xa.,function:Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.,online information:TFPI entry,PTM:O-glycosylated.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,similarity:Contains 3 BPTI/Kunitz inhibitor domains.,tissue specificity:Mostly in endothelial cells.,

• 功能：
• blood coagulation, blood coagulation, extrinsic pathway, hemostasis, response to wounding, wound healing,coagulation, regulation of body fluid levels,

• 细胞定位：
• [Isoform Alpha]: Secreted.; [Isoform Beta]: Microsome membrane ; Lipid-anchor, GPI-anchor .

• 组织表达：
• Mostly in endothelial cells.

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