Human Mesothelin ELISA Kit
- 货号：KE1236
- 应用：ELISA
- 种属：Human
- 特异性：
- Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
- 其他名称：
- MSLN;MPF;Mesothelin;CAK1 antigen;Pre-pro-megakaryocyte-potentiating factor
- 背景：
- disease:Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.,function:Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.,function:Membrane-anchored forms may play a role in cellular adhesion.,PTM:Both MPF and the cleaved form of mesothelin are N-glycosylated.,PTM:Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.,similarity:Belongs to the mesothelin family.,subunit:Interacts with MUC16.,tissue specificity:Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).,
- 功能：
- cell adhesion, biological adhesion,
- 细胞定位：
- Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus.; [Megakaryocyte-potentiating factor]: Secreted.; [Isoform 3]: Secreted.
- 组织表达：
- Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).
- The Human Mesothelin ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Mesothelin proteins within the range of 250-8000 pg/ml.
