Human Angiopoietin-Like 3 ELISA Kit
- 货号：KE1196
- 应用：ELISA
- 种属：Human
- 蛋白名称：
- Angiopoietin-related protein 3
- 特异性：
- Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
- 其他名称：
- ANGPTL3;ANGPT5;Angiopoietin-related protein 3;Angiopoietin-5;ANG-5;Angiopoietin-like protein 3
- 背景：
- similarity:Contains 1 fibrinogen C-terminal domain.,tissue specificity:Expressed principally in liver. Weakly expressed in kidney.,
- 功能：
- blood vessel development, vasculature development, glycerol metabolic process, fatty acid metabolic process,phospholipid metabolic process, cell adhesion, cell-matrix adhesion, cell surface receptor linked signal transduction,integrin-mediated signaling pathway, steroid metabolic process, cholesterol metabolic process, phospholipid catabolic process, regulation of catabolic process, positive regulation of catabolic process, regulation of phospholipase activity,negative regulation of phospholipase activity, lipid localization, lipid catabolic process, sterol metabolic process,regulation of lipid metabolic process, alditol metabolic process, organophosphate metabolic process, polyol metabolic process, lipid storage, biological adhesion, regulation of cell migration, positive regulation of cell migration, cell-substrate adhesion, regulation of locomotion, positive regulation of locomotion,
- 细胞定位：
- Secreted . Cell projection, lamellipodium . Colocalized with HSPG2 and activated ITGB3 on podocytes. .
- 组织表达：
- Expressed principally in liver. Weakly expressed in kidney. Binds to adipocytes. Increased expression and colocalization with activated ITGB3 in glomeruli of patients with nephrotic syndrome showing effaced podocyte foot processes (at protein level).
- The Human Angiopoietin-Like 3 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Angiopoietin-Like 3 proteins within the range of 32-2000 pg/ml.
