• 基因名称：
• CXCL10

• 蛋白名称：
• C-X-C motif chemokine 10

• Human Gene Id：
• 3627

• Human Swiss Prot No：
• P02778

• Mouse Swiss Prot No：
• P17515

• 特异性：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• 储存：
• 2-8°C/6 months

• 其他名称：
• CXCL10;INP10;SCYB10;C-X-C motif chemokine 10;10 kDa interferon gamma-induced protein;Gamma-IP10;IP-10;Small-inducible cytokine B10

• 检测方法：
• Colorimetric

• 背景：
• function:Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.,induction:By interferon gamma. A diverse population of cell types rapidly increases transcription of mRNA encoding this protein. This suggests that gamma-induced protein may be a key mediator of the interferon gamma response.,mass spectrometry: PubMed:11559369,online information:CXCL10 entry,PTM:CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,

• 功能：
• circulatory system process, chemotaxis, defense response, inflammatory response, immune response, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, cell-cell signaling, muscle organ development, behavior, locomotory behavior, blood circulation, protein localization, positive regulation of cell proliferation, protein secretion, response to wounding, protein transport, regulation of cell migration, positive regulation of cell migration, secretion by cell, regulation of locomotion, positive regulation of locomotion, regulation of cell proliferation, taxis, establishment of protein localization, secretion, regulation of cell motion, positive regulation of cell motion,

• 细胞定位：
• Secreted .

• 组织表达：
• Mainly secreted by monocytes, endothelial cells as well as fibroblasts. Expressed by epithelial cells in thymus (PubMed:11157474). Microglial cells produce CXCL10 in response to viral stimulation (PubMed:12663757).

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