• 基因名称：
• IL21

• 蛋白名称：
• Interleukin-21

• Human Gene Id：
• 59067

• Human Swiss Prot No：
• Q9HBE4

• Mouse Swiss Prot No：
• Q9ES17

• 特异性：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• 储存：
• 2-8°C/6 months

• 其他名称：
• IL21;Interleukin-21;IL-21;Za11

• 检测方法：
• Colorimetric

• 背景：
• function:Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.,similarity:Belongs to the IL-15/IL-21 family.,tissue specificity:Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.,

• 功能：
• regulation of cytokine production, positive regulation of cytokine production, regulation of leukocyte mediated cytotoxicity, positive regulation of leukocyte mediated cytotoxicity, positive regulation of immune system process,regulation of leukocyte activation, positive regulation of leukocyte activation, regulation of immune effector process,positive regulation of immune effector process, regulation of production of molecular mediator of immune response,positive regulation of production of molecular mediator of immune response, regulation of leukocyte mediated immunity, positive regulation of leukocyte mediated immunity, regulation of lymphocyte mediated immunity, positive regulation of lymphocyte mediated immunity, regulation of natural killer cell mediated immunity, positive regulation of natural killer cell mediated immunity, regulation of cytokine production during immune response,

• 细胞定位：
• Secreted .

• 组织表达：
• Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.

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