Total GK3 Cell-Based Colorimetric ELISA Kit
- 货号：KA4355C
- 应用：ELISA
- 种属：Human
- 背景：
- catalytic activity:ATP + glycerol = ADP + sn-glycerol 3-phosphate.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,disease:Defects in GK are the cause of GK deficiency (GKD) [MIM:307030]. This disease can be either symptomatic with episodic metabolic and CNS decompensation or asymptomatic with hyperglycerolemia and hyperglyceroluria only.,function:Key enzyme in the regulation of glycerol uptake and metabolism.,pathway:Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.,similarity:Belongs to the FGGY kinase family.,subcellular location:In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.,tissue specificity:Highly expressed in the liver, kidney and testis. Isoforms 2 and 3 are expressed specifically in testis and fetal liver, but not in the adult liver.,
- 细胞定位：
- Mitochondrion outer membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm . In sperm the majority of the enzyme is bound to mitochondria. .
