• 基因名称：
• FADD

• Human Gene Id：
• 14082

• Human Swiss Prot No：
• Q61160

• 储存：
• 2-8°C/6 months

• 检测方法：
• Colorimetric

• 背景：
• Q61160 Fas (TNFRSF6)-associated via death domain(Fadd) Mus musculus domain:Contains a death domain involved in the binding of the corresponding domain within Fas receptor.,function:Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.,PTM:Phosphorylated.,similarity:Contains 1 death domain.,similarity:Contains 1 DED (death effector) domain.,subunit:Interacts with CFLAR, PEA15 and MBD4. When phosphorylated, part of a complex containing HIPK3 and FAS. May interact with MAVS/IPS1. Interacts with LRDD.,

• 功能：
• apoptosis, cell death, regulation of cell death, programmed cell death, death, regulation of apoptosis, regulation of programmed cell death,

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