Phospho MNK1 (T385) Cell-Based Colorimetric ELISA Kit

  • 货号：KA1755C
  • 应用：ELISA
  • 种属：Human;Mouse;Rat
    • 基因名称：
    • MKNK1
    • Human Gene Id：
    • 8569
    • Human Swiss Prot No：
    • Q9BUB5
    • Mouse Swiss Prot No：
    • O08605
    • 储存：
    • 2-8°C/6 months
    • 其他名称：
    • MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)
    • 检测方法：
    • Colorimetric
    • 背景：
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Phosphorylated and activated by the p38 kinases and kinases in the Erk pathway.,function:May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.,PTM:Dual phosphorylation of Thr-250 and Thr-255 activates the kinase. Phosphorylation of Thr-385 activates the kinase.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with the C-terminal regions of EIF4G1 and EIF4G2. Also binds to dephosphorylated ERK1 and ERK2, and to the p38 kinases.,tissue specificity:Ubiquitous.,
    • 功能：
    • regulation of translation, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, protein kinase cascade, posttranscriptional regulation of gene expression,phosphorylation, regulation of cellular protein metabolic process,
    • 细胞定位：
    • [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.
    • 组织表达：
    • Ubiquitous.

    相关报价

    • 货号：
    • KA1755C
    • 规格：
    • 96 / well
    • 价格：
    • ¥4700
    • 货期：
    • 预计发货时间为
      2024-12-08
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