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Phospho STAT5A/B (S725/730) Cell-Based Colorimetric ELISA Kit

背景：
function:Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.,online information:STAT5 entry,PTM:Tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity.,similarity:Belongs to the transcription factor STAT family.,similarity:Contains 1 SH2 domain.,subcellular location:Translocated into the nucleus in response to phosphorylation.,subunit:Forms a homodimer or a heterodimer with a related family member. Binds NR3C1 (By similarity). Interacts with NCOA1 and SOCS7.,

功能：
allantoin metabolic process, luteinization, cell activation, leukocyte homeostasis, natural killer cell differentiation,regulation of cytokine production, regulation of leukocyte mediated cytotoxicity, positive regulation of leukocyte mediated cytotoxicity, lymphocyte homeostasis, immune system development, leukocyte differentiation, positive regulation of immune system process, regulation of leukocyte activation, positive regulation of leukocyte activation,regulation of immune effector process, positive regulation of immune effector process, regulation of leukocyte mediated immunity, positive regulation of leukocyte mediated immunity, regulation of lymphocyte mediated immunity,positive regulation of lymphocyte mediated immunity, regulation of natural killer cell mediated immunity, positive regulation of natural killer cell mediated immunity, regulation of myeloid leukocyte differentiati

细胞定位：
Cytoplasm . Nucleus . Translocated into the nucleus in response to phosphorylation.