Phospho MAP3K8 (T290) Cell-Based Colorimetric ELISA Kit

  • 货号：KA1202C
  • 应用：ELISA
  • 种属：Human;Mouse;Rat
    • 基因名称：
    • MAP3K8
    • Human Gene Id：
    • 1326
    • Human Swiss Prot No：
    • P41279
    • Mouse Swiss Prot No：
    • Q07174
    • 储存：
    • 2-8°C/6 months
    • 其他名称：
    • Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (Cancer Osaka thyroid oncogene) (Proto-oncogene c-Cot) (Serine/threonine-protein kinase cot) (Tumor progression locus 2) (TPL-2)
    • 检测方法：
    • Colorimetric
    • 背景：
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,developmental stage:Isoform 1 is activated specifically during the S and G2/M phases of the cell cycle.,function:Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle. The longer form has some transforming activity, although it is much weaker than the activated cot oncoprotein.,PTM:Autophosphorylated. Isoform 1 undergoes phosphorylation mainly on Ser residues, and isoform 2 on both Ser and Thr residues.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Forms a ternary complex with NFKB1 and TNIP2.,tissue specificity:Expressed in several normal tissues and human tumor-derived cell lines.,
    • 功能：
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell cycle,phosphorylation,
    • 细胞定位：
    • Cytoplasm .
    • 组织表达：
    • Expressed in several normal tissues and human tumor-derived cell lines.

    相关报价

    • 货号：
    • KA1202C
    • 规格：
    • 96 / well
    • 价格：
    • ¥4700
    • 货期：
    • 预计发货时间为
      2024-12-08
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