• 靶点：
• PSAP

• 基因名称：
• ACPP

• 蛋白名称：
• PSAP

• Human Gene Id：
• 55

• Human Swiss Prot No：
• P15309

• 免疫原：
• Synthesized peptide derived from human PSAP AA range: 201-300

• 特异性：
• The antibody can specifically recognize human PSAP protein.

• 来源：
• Mouse, Monoclonal/IgG2b, kappa

• 纯化工艺：
• The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

• 储存：
• 2°C to 8°C/1 year

• 其他名称：
• Prostatic acid phosphatase (PAP;EC 3.1.3.2;5'-nucleotidase;5'-NT;EC 3.1.3.5;Ecto-5'-nucleotidase;Thiamine monophosphatase;TMPase) [Cleaved into: PAPf39]

• 背景：
• This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008],

• 功能：
• catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,similarity:Belongs to the histidine acid phosphatase family.,subcellular location:Predominantly localized in the plasma membrane but also detected in intracellular vesicles.,subunit:Homodimer.,

• 细胞定位：
• Cytoplasmic

• 组织表达：
• Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Low expression in prostate carcinoma cells and tissues. ; [Isoform 2]: Widely expressed. Expressed in the sarcolemma of skeletal muscle.

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