S100A4 (ABT-S100A4) IHC kit
- 货号：IHCM6216
- 应用：IHC
- 种属：Human;
- 蛋白名称：
- Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4)
- 免疫原：
- Synthesized peptide derived from human S100A4 AA range: 50-101
- 特异性：
- The antibody can specifically recognize human S100A4 protein, and has no cross reaction with S100A1 or S100A6.
- 来源：
- Mouse, Monoclonal/IgG1, kappa
- 纯化工艺：
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- 背景：
- S100 calcium binding protein A4(S100A4) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
- 功能：
- similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer. Interacts with PPFIBP1 in a calcium-dependent mode.,tissue specificity:Ubiquitously expressed.,
- 细胞定位：
- Nuclear, Cytoplasmic
- 组织表达：
- Ubiquitously expressed.
- Human malignant melanoma tissue was stained with Anti-S100A4 (ABT-S100A4) Antibody
- Human tonsil tissue was stained with Anti-S100A4 (ABT-S100A4) Antibody
