Synaptophysin (ABT533) IHC kit
- 货号：IHCM6105
- 应用：IHC
- 种属：Human;Mouse;Rat;Bovin;
- 蛋白名称：
- Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI
- 免疫原：
- Synthesized peptide derived from human Synaptophysin AA range: 200-313
- 特异性：
- The antibody can specifically recognize human Synaptophysin protein.
- 来源：
- Mouse, Monoclonal/IgG1, kappa
- 纯化工艺：
- The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
- 其他名称：
- Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI
- 背景：
- This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011],
- 功能：
- domain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.,function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.,online information:Synaptophysin entry,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the synaptophysin/synaptobrevin family.,similarity:Contains 1 MARVEL domain.,subunit:Homohexamer or homotetramer.,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.,
- Human adrenal gland tissue was stained with Anti-Synaptophysin (ABT533) Antibody
- Human pancreas tissue was stained with Anti-Synaptophysin (ABT533) Antibody
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- Human pancreas tissue was stained with Anti-Synaptophysin (ABT533) Antibody
