Catalog: YN2546
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
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0
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Main Information
Target
GNRR2
Host Species
Rabbit
Reactivity
Human
Applications
WB, ELISA
MW
32kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
GNRR2 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
32kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 10-90
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Specificity:
GNRR2 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
GNRHR2
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Protein Name:
Putative gonadotropin-releasing hormone II receptor (GnRH II receptor) (GnRH-II-R) (Type II GnRH receptor)
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Database Link:
| Organism | Gene ID | SwissProt |
|---|---|---|
| Human | Q96P88; |
Background:
In non-hominoid primates and non-mammalian vertebrates, the gonadotropin releasing hormone 2 receptor gene (GnRHR2) encodes a seven-transmembrane G-protein coupled receptor. However, in human, the corresponding reading frame contains a premature stop codon, which has been suggested to encode a selenocysteine residue, but there is no solid evidence for selenocysteine incorporation (PMID: 12538601). It appears that the human GnRHR2 transcription occurs but the gene does not likely produce a functional multi-transmembrane protein. A non-transcribed pseudogene of GnRHR2 is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2013],
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Function:
Caution:Could be the product of a pseudogene. This protein seems to be substantially shorter than orthologous proteins in related organisms.,Function:Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system .,PTM:Phosphorylated on the C-terminal cytoplasmic tail.,sequence Caution:Translated as stop.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in many tissues.,
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Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Tissue Expression:
Expressed in many tissues.
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Reference Citation({{totalcount}})
Catalog: YN2546
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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