Catalog: YT6346
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
DEGS2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
36kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of DEGS2 at Human/Mouse/Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
36kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human DEGS2 AA range: 92-142
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Specificity:
This antibody detects endogenous levels of DEGS2 at Human/Mouse/Rat
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Gene Name:
DEGS2 C14orf66
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Protein Name:
DEGS2
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Database Link:
Background:
This gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase. [provided by RefSeq, Oct 2008],
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Function:
Function:Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase.,induction:Up-regulated during keratinocyte differentiation. Not expressed at day 0 or day 3 after differentiation, detected on day 6 and increases by day 9.,pathway:Membrane lipid metabolism; sphingolipid biosynthesis.,similarity:Belongs to the fatty acid desaturase family. DEGS subfamily.,tissue specificity:Highly expressed in skin, intestine and kidney.,
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Cellular Localization:
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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Tissue Expression:
Highly expressed in skin, intestine and kidney.
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Research Areas:
>>Sphingolipid metabolism ;
>>Metabolic pathways ;
>>Sphingolipid signaling pathway
>>Metabolic pathways ;
>>Sphingolipid signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT6346
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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