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Catalog: YT3751
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Main Information
Target

PKAγ cat

Host Species

Rabbit

Reactivity

Human

Applications

WB, IHC, IF, ELISA

MW

40kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
PKAγ cat Polyclonal Antibody detects endogenous levels of PKAγ cat protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
40kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human KAPCG. AA range:1-50
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Specificity:
PKAγ cat Polyclonal Antibody detects endogenous levels of PKAγ cat protein.
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Gene Name:
PRKACG
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Protein Name:
cAMP-dependent protein kinase catalytic subunit gamma
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Other Name:
PRKACG ;
cAMP-dependent protein kinase catalytic subunit gamma ;
PKA C-gamma
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Database Link:
Organism Gene ID SwissProt
Human 5568; P22612;
Background:
Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008],
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Function:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by cAMP.,Function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,subunit:A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.,tissue specificity:Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.,
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Cellular Localization:
nucleoplasm,cytosol,ciliary base,
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Tissue Expression:
Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.
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Research Areas:
>>Endocrine resistance ;
>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Calcium signaling pathway ;
>>cAMP signaling pathway ;
>>Chemokine signaling pathway ;
>>Oocyte meiosis ;
>>Autophagy - animal ;
>>Longevity regulating pathway ;
>>Longevity regulating pathway - multiple species ;
>>Adrenergic signaling in cardiomyocytes ;
>>Vascular smooth muscle contraction ;
>>Wnt signaling pathway ;
>>Hedgehog signaling pathway ;
>>Apelin signaling pathway ;
>>Tight junction ;
>>Gap junction ;
>>Platelet activation ;
>>Circadian entrainment ;
>>Thermogenesis ;
>>Long-term potentiation ;
>>Retrograde endocannabinoid signaling ;
>>Glutamatergic synapse ;
>>Cholinergic synapse ;
>>Serotonergic synapse ;
>>GABAergic synapse ;
>>Dopaminergic synapse ;
>>Olfactory transduction ;
>>Taste transduction ;
>>Inflammatory mediator regulation of TRP channels ;
>>Insulin signaling pathway ;
>>Insulin secretion ;
>>GnRH signaling pathway ;
>>Ovarian steroidogenesis ;
>>Progesterone-mediated oocyte maturation ;
>>Estrogen signaling pathway ;
>>Melanogenesis ;
>>Thyroid hormone synthesis ;
>>Thyroid hormone signaling pathway ;
>>Oxytocin signaling pathway ;
>>Glucagon signaling pathway ;
>>Regulation of lipolysis in adipocytes ;
>>Renin secretion ;
>>Aldosterone synthesis and secretion ;
>>Relaxin signaling pathway ;
>>Cortisol synthesis and secretion ;
>>Parathyroid hormone synthesis, secretion and action ;
>>Cushing syndrome ;
>>Growth hormone synthesis, secretion and action ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Vasopressin-regulated water reabsorption ;
>>Salivary secretion ;
>>Gastric acid secretion ;
>>Bile secretion ;
>>Parkinson disease ;
>>Prion disease ;
>>Cocaine addiction ;
>>Amphetamine addiction ;
>>Morphine addiction ;
>>Alcoholism ;
>>Vibrio cholerae infection ;
>>Amoebiasis ;
>>Human cytomegalovirus infection ;
>>Human papillomavirus infection ;
>>Human T-cell leukemia virus 1 infection ;
>>Pathways in cancer ;
>>Viral carcinogenesis ;
>>Proteoglycans in cancer ;
>>Chemical carcinogenesis - receptor activation ;
>>Dilated cardiomyopathy
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Signaling Pathway
Cellular Processes >> Transport and catabolism >> Autophagy - animal Cellular Processes >> Cellular community - eukaryotes >> Tight junction Cellular Processes >> Cellular community - eukaryotes >> Gap junction Organismal Systems >> Immune system >> Platelet activation Organismal Systems >> Immune system >> Chemokine signaling pathway Organismal Systems >> Endocrine system >> Insulin secretion Organismal Systems >> Endocrine system >> Insulin signaling pathway Organismal Systems >> Endocrine system >> Glucagon signaling pathway Organismal Systems >> Endocrine system >> GnRH signaling pathway Organismal Systems >> Endocrine system >> Estrogen signaling pathway Organismal Systems >> Endocrine system >> Oxytocin signaling pathway Organismal Systems >> Endocrine system >> Relaxin signaling pathway Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway Organismal Systems >> Endocrine system >> Aldosterone synthesis and secretion Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction Organismal Systems >> Nervous system >> Glutamatergic synapse Organismal Systems >> Nervous system >> Cholinergic synapse Organismal Systems >> Nervous system >> Dopaminergic synapse Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels Organismal Systems >> Aging >> Longevity regulating pathway Organismal Systems >> Aging >> Longevity regulating pathway - multiple species Human Diseases >> Cancer: overview >> Pathways in cancer Human Diseases >> Neurodegenerative disease >> Parkinson disease Human Diseases >> Neurodegenerative disease >> Prion disease Environmental Information Processing >> Signal transduction >> MAPK signaling pathway Environmental Information Processing >> Signal transduction >> Ras signaling pathway Environmental Information Processing >> Signal transduction >> Wnt signaling pathway Environmental Information Processing >> Signal transduction >> Hedgehog signaling pathway Environmental Information Processing >> Signal transduction >> Apelin signaling pathway Environmental Information Processing >> Signal transduction >> Calcium signaling pathway Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
Catalog: YT3751
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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