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Catalog: YN0754
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Main Information
Target

GBB1

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, ELISA

MW

37kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
GBB1 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
37kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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RS0002

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β-actin (PTR2364) Mouse mAb
YM3028

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GAPDH (PTR2304) Mouse mAb
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
GBB1 Polyclonal Antibody detects endogenous levels of protein.
show all
Gene Name:
GNB1
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Protein Name:
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
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Database Link:
Organism Gene ID SwissProt
Human 2782; P62873;
Mouse P62874;
Rat P54311;
Background:
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
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Function:
Function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the WD repeat G protein beta family.,similarity:Contains 7 WD repeats.,subunit:G proteins are composed of 3 units, alpha, beta and gamma. Interacts with ARHGEF18.,
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Cellular Localization:
photoreceptor inner segment,intracellular,lysosomal membrane,cytosol,heterotrimeric G-protein complex,plasma membrane,membrane,dendrite,photoreceptor outer segment membrane,myelin sheath,cell body,extracellular exosome,
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Tissue Expression:
B-cell lymphoma,Brain,Fetal brain cortex,Liver,Melanoma,Muscle,Ovarian carcinoma,PC
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Research Areas:
>>Ras signaling pathway ;
>>Chemokine signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Apelin signaling pathway ;
>>Circadian entrainment ;
>>Retrograde endocannabinoid signaling ;
>>Glutamatergic synapse ;
>>Cholinergic synapse ;
>>Serotonergic synapse ;
>>GABAergic synapse ;
>>Dopaminergic synapse ;
>>Olfactory transduction ;
>>Phototransduction ;
>>Relaxin signaling pathway ;
>>Morphine addiction ;
>>Alcoholism ;
>>Human cytomegalovirus infection ;
>>Kaposi sarcoma-associated herpesvirus infection ;
>>Human immunodeficiency virus 1 infection ;
>>Pathways in cancer
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Catalog: YN0754
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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