Catalog: YM1061
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
MAP-2
Host Species
Mouse
Reactivity
Human, Mouse, Rat, Bovine, Pig
Applications
WB, IF
MW
200kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:1000-1:2000; IF 1:100-1:500; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
MAP-2 Monoclonal Antibody detects endogenous levels of MAP-2 protein.
Purification
Affinity purification
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
200kD
Modification
Unmodified
Clonality
Monoclonal
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Antigen&Target Information
Immunogen:
Purified recombinant human MAP-2 (N-terminus) protein fragments expressed in E.coli.
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Specificity:
MAP-2 Monoclonal Antibody detects endogenous levels of MAP-2 protein.
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Gene Name:
MAP2
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Protein Name:
Microtubule-associated protein 2
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Other Name:
MAP2 ;
Microtubule-associated protein 2 ;
MAP-2
Microtubule-associated protein 2 ;
MAP-2
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Background:
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010],
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Function:
Alternative products:Additional isoforms seem to exist,Function:The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.,PTM:MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 Tau/MAP repeats.,similarity:Contains 4 Tau/MAP repeats.,
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Cellular Localization:
Cytoplasm, cytoskeleton . Cell projection, dendrite .
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Tissue Expression:
Brain,Brain cortex,Epithelium,Pancreas,Testis,
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Reference Citation({{totalcount}})
Catalog: YM1061
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
Add to cart
Collected
Collect
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