Catalog: YT2552
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
LDOC1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
IHC, IF, ELISA
MW
17kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
LDOC1 Polyclonal Antibody detects endogenous levels of LDOC1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
17kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human LDOC1. AA range:21-70
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Specificity:
LDOC1 Polyclonal Antibody detects endogenous levels of LDOC1 protein.
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Gene Name:
LDOC1
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Protein Name:
Protein LDOC1
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Other Name:
LDOC1 ;
BCUR1 ;
Protein LDOC1 ;
Leucine zipper protein down-regulated in cancer cells
BCUR1 ;
Protein LDOC1 ;
Leucine zipper protein down-regulated in cancer cells
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Background:
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008],
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Function:
Function:May have an important role in the development and/or progression of some cancers.,similarity:Belongs to the LDOC1 family.,tissue specificity:Ubiquitously expressed with high levels in brain ant thyroid and low expression in placenta, liver and leukocytes. Expressed as well in six of the seven human breast cancer cell lines examined.,
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Cellular Localization:
Nucleus .
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Reference Citation({{totalcount}})
Catalog: YT2552
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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