Catalog: YT1856
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
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0
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Main Information
Target
GASP-1
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
IHC, IF, ELISA
MW
157kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
GASP-1 Polyclonal Antibody detects endogenous levels of GASP-1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
157kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human GASP1. AA range:741-790
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Specificity:
GASP-1 Polyclonal Antibody detects endogenous levels of GASP-1 protein.
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Gene Name:
GPRASP1
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Protein Name:
G-protein coupled receptor-associated sorting protein 1
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Other Name:
GPRASP1 ;
GASP ;
KIAA0443 ;
G-protein coupled receptor-associated sorting protein 1 ;
GASP-1
GASP ;
KIAA0443 ;
G-protein coupled receptor-associated sorting protein 1 ;
GASP-1
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Background:
This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010],
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Function:
Function:May modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes.,similarity:Belongs to the GPRASP family.,subunit:Interacts with cytoplasmic tails of a variety of G-protein coupled receptors such as D2 dopamine receptor/DRD2 (By similarity), delta opioid receptor/OPRD1, beta-2 adrenergic receptor/ADRB2 and D4 dopamine receptor/DRD4. Interacts with PER1.,tissue specificity:Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.,
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Cellular Localization:
Cytoplasm .
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Tissue Expression:
Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.
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Reference Citation({{totalcount}})
Catalog: YT1856
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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