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Catalog: YN2100
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
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0

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Main Information
Target

TFR2

Host Species

Rabbit

Reactivity

Human, Rat, Mouse

Applications

WB, ELISA

MW

22kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
RASM Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
22kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
RASM Polyclonal Antibody detects endogenous levels of protein.
show all
Gene Name:
MRAS RRAS3
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Protein Name:
Ras-related protein M-Ras (Ras-related protein R-Ras3)
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Database Link:
Organism Gene ID SwissProt
Human 22808; O14807;
Mouse O08989;
Rat P97538;
Background:
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
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Function:
Function:May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.,induction:By interleukin-9, but not by IL-2 or IL-4.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with RGL3.,tissue specificity:Expression highly restricted to the brain and heart.,
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Cellular Localization:
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
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Tissue Expression:
Expression highly restricted to the brain and heart.
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Research Areas:
>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>Phospholipase D signaling pathway ;
>>Mitophagy - animal ;
>>Autophagy - animal ;
>>Cellular senescence ;
>>Apelin signaling pathway ;
>>C-type lectin receptor signaling pathway ;
>>Regulation of actin cytoskeleton ;
>>Proteoglycans in cancer
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Catalog: YN2100
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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