DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al., 2003 [PubMed 12738806]).[supplied by OMIM, Mar 2008],
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Function:
Catalytic activity:Hydrolysis of dipeptides.,cofactor:Zinc.,enzyme regulation:Inhibited by L-penicillamine.,Function:Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).,similarity:Belongs to the peptidase M19 family.,subunit:Homodimer; disulfide-linked.,