Catalog: YT6651
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
ITM2C
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
MW
29kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of ITM2C at Human/Mouse/Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
29kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human ITM2C AA range: 1-51
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Specificity:
This antibody detects endogenous levels of ITM2C at Human/Mouse/Rat
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Gene Name:
ITM2C BRI3 hucep-14 NPD018 PSEC0047
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Protein Name:
ITM2C
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Database Link:
Function:
PTM:Type I membrane-bound, as well as soluble, furin has a pre-eminent role in ITM2C proteolytic processing. PCSK7 and PCSK5 may also be involved although to a lesser extent. The soluble form of PCSK7 is incapable of processing ITM2C.,similarity:Belongs to the ITM2 family.,similarity:Contains 1 BRICHOS domain.,subunit:Interacts with BACE1.,tissue specificity:High levels in the brain, specifically in the cerebral cortex, medulla, amygdala, hippocampus, thalamus, caudate nucleus, cerebellum, olfactory lobe and spinal cord. Very low levels in other organs.,
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Cellular Localization:
Lysosome membrane ; Single-pass type II membrane protein . Cell membrane ; Single-pass type II membrane protein .
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Tissue Expression:
High levels in the brain, specifically in the cerebral cortex, medulla, amygdala, hippocampus, thalamus, caudate nucleus, cerebellum, olfactory lobe and spinal cord. Very low levels in other organs.
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Reference Citation({{totalcount}})
Catalog: YT6651
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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