Catalog: YN7755
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
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Main Information
Target
GUCA1B
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
22kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of GCAP2 at Human, Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
22kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human GCAP2
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Specificity:
This antibody detects endogenous levels of GCAP2 at Human, Mouse
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Gene Name:
GUCA1B GCAP2
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Protein Name:
Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B)
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Function:
Stimulates two retinal guanylyl cyclases (GCs) GUCY2D and GUCY2F when free calcium ions concentration is low, and inhibits GUCY2D and GUCY2F when free calcium ions concentration is elevated (By similarity). This Ca(2+)-sensitive regulation of GCs is a key event in recovery of the dark state of rod photoreceptors following light exposure (By similarity). May be involved in cone photoreceptor response and recovery of response in bright light (By similarity).
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Cellular Localization:
Cell membrane ; Lipid-anchor . Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . Subcellular location is not affected by light or dark conditions. .
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Tissue Expression:
In the retina, it is expressed in cone and rod photoreceptor cells.
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Reference Citation({{totalcount}})
Catalog: YN7755
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
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