Catalog: YN3106
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
ATX3L
Host Species
Rabbit
Reactivity
Human
Applications
WB
MW
38kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of ATX3L at Human
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
38kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human ATX3L AA range: 99-149
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Specificity:
This antibody detects endogenous levels of ATX3L at Human
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Gene Name:
ATXN3L ATX3L MJDL
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Protein Name:
ATX3L
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Other Name:
Putative ataxin-3-like protein ;
Machado-Joseph disease protein 1-like ;
Machado-Joseph disease protein 1-like ;
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Background:
This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease. [provided by RefSeq, Sep 2011],
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Function:
Caution:Could be the product of a pseudogene. Suggested by the absence of intron.,Function:May bind to histones and regulate transcription. May act as a deubiquitinating enzyme.,similarity:Contains 1 Josephin domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats.,
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Cellular Localization:
Nucleus .
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Tissue Expression:
Testis,
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Research Areas:
>>Protein processing in endoplasmic reticulum ;
>>Spinocerebellar ataxia ;
>>Pathways of neurodegeneration - multiple diseases
>>Spinocerebellar ataxia ;
>>Pathways of neurodegeneration - multiple diseases
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN3106
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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