Synthesized peptide derived from human protein . at AA range: 480-560

ACOX3 Polyclonal Antibody detects endogenous levels of protein.

ACOX3 BRCOX PRCOX

Peroxisomal acyl-coenzyme A oxidase 3 (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase)

Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008],

Catalytic activity:Acyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2).,cofactor:FAD.,Function:Oxidizes the CoA-esters of 2-methyl-branched fatty acids.,pathway:Lipid metabolism; peroxisomal fatty acid beta-oxidation.,similarity:Belongs to the acyl-CoA oxidase family.,

Peroxisome .

Liver,Uterus,

>>Fatty acid degradation ;
>>beta-Alanine metabolism ;
>>alpha-Linolenic acid metabolism ;
>>Propanoate metabolism ;
>>Biosynthesis of unsaturated fatty acids ;
>>Metabolic pathways ;
>>Carbon metabolism ;
>>Fatty acid metabolism ;
>>PPAR signaling pathway ;
>>cAMP signaling pathway ;
>>Peroxisome ;
>>Alcoholic liver disease