Catalog: YM4710
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
PAX2
Host Species
Mouse
Reactivity
Human,
Applications
IHC, IF, ELISA
MW
45kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:200-1000; IF 1:100-500; ELISA 1:1000-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
This antibody detects endogenous levels of PAX2 protein.
Purification
Protein G
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
45kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PTR1301
Isotype
IgG1,Kappa
Antigen&Target Information
Immunogen:
Synthesized peptide derived from human PAX2. AA range: 150-250
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Specificity:
This antibody detects endogenous levels of PAX2 protein.
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Gene Name:
PAX2
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Protein Name:
Paired box protein Pax-2
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Other Name:
Paired box protein Pax-2
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Background:
paired box 2(PAX2) Homo sapiens PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014],
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Function:
Transcription factor that may have a role in kidney cell differentiation . Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
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Cellular Localization:
Nuclear
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Tissue Expression:
Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.
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Reference Citation({{totalcount}})
Catalog: YM4710
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
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