Catalog: YA0209
Size
Price
Status
Qty.
200μg
$600.00
3 weeks
0
100μg
$340.00
3 weeks
0
40μg
$190.00
3 weeks
0
Add to cart
Collected
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Main Information
Target
CD371
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
ELISA 1:5000-100000
Formulation
Phosphate-buffered solution
Source
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Specificity
This recombinant monoclonal antibody can detects endogenous levels of CD371 protein.
Purification
Recombinant Expression and Affinity purified
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration
Please check the information on the tube
Modification
Unmodified
Clone Number
PN0193
Related Products
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Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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Antigen&Target Information
Immunogen:
Purified recombinant Human CD371
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Specificity:
This recombinant monoclonal antibody can detects endogenous levels of CD371 protein.
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Gene Name:
CLEC12A CLL1 DCAL2 MICL
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Protein Name:
C-type lectin domain family 12 member A (C-type lectin-like molecule 1) (CLL-1) (Dendritic cell-associated lectin 2) (DCAL-2) (Myeloid inhibitory C-type lectin-like receptor) (MICL) (CD antigen CD371)
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Other Name:
CLL1 ;
MICL ;
CLL-1 ;
DCAL-2 ;
C-type lectin domain family 12 member A ;
CD371 ;
CD371 nanobody ;
MICL ;
CLL-1 ;
DCAL-2 ;
C-type lectin domain family 12 member A ;
CD371 ;
CD371 nanobody ;
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Background:
CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family. It is expressed on monocytes, granulocytes, NK cells, and basophils. Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases.
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Function:
Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
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Cellular Localization:
Cell membrane ; Single-pass type II membrane protein . Ligand binding leads to internalization.
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Tissue Expression:
Thymus
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Signaling Pathway
Organismal Systems >> Immune system >> Hematopoietic cell lineage
Organismal Systems >> Immune system >> Th1 and Th2 cell differentiation
Organismal Systems >> Immune system >> Th17 cell differentiation
Human Diseases >> Cancer: overview >> Pathways in cancer
Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
Reference Citation({{totalcount}})
Catalog: YA0209
Size
Price
Status
Qty.
200μg
$600.00
3 weeks
0
100μg
$340.00
3 weeks
0
40μg
$190.00
3 weeks
0
Add to cart
Collected
Collect
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