Catalog: YD2195
Size
Price
Status
Qty.
1mg
$18,000.00
3 weeks
0
100μg
$600.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Reactivity
Human
Applications
ELISA, ECL, Immunogold,
MW
86kD (Calculated)
100-110kD (Observed)
Detailed Information
Recommended Dilution Ratio
Testing in progress
Source
Mammalian cells
Purity
>90% as determined by SDS-PAGE
Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
MW(Calculated)
86kD
MW(Observed)
100-110kD
Antigen&Target Information
Gene Name:
ACE2
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Protein Name:
ACE-related carboxypeptidase
Angiotensin-converting enzyme homolog
Metalloprotease MPROT15
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Database Link:
| Organism | Gene ID | SwissProt |
|---|---|---|
| Human | NP_001358344.1 or Q9BYF1; | Q9BYF1; |
| Mouse | Q8R0I0; |
Background:
Recombinant Human ACE2 is produced by Mammalian cells expression system and the target gene encoding Met1-Ser740 is expressed with C-HisTag
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Function:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
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Research Areas:
For research use only .Not for use in clinical diagnostic procedures.
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Reference Citation({{totalcount}})
Catalog: YD2195
Size
Price
Status
Qty.
1mg
$18,000.00
3 weeks
0
100μg
$600.00
3 weeks
0
Add to cart
Collected
Collect
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