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Catalog: YT2978
Size
Price
Status
Qty.
200μL
$450.00
In stock

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100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Main Information
Target

Nap1

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

48kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Nap1 Polyclonal Antibody detects endogenous levels of Nap1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
48kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human AZI2. AA range:10-59
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Specificity:
Nap1 Polyclonal Antibody detects endogenous levels of Nap1 protein.
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Gene Name:
AZI2
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Protein Name:
5-azacytidine-induced protein 2
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Other Name:
AZI2 ;
NAP1 ;
5-azacytidine-induced protein 2 ;
NF-kappa-B-activating kinase-associated protein 1 ;
Nak-associated protein 1 ;
TILP
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Database Link:
Organism Gene ID SwissProt
Human 64343; Q9H6S1;
Mouse 27215; Q9QYP6;
Rat 316051; Q4KMA0;
Background:
AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008],
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Function:
Function:Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1.,subunit:Interacts with IKBKE, TBK1 and TICAM1.,tissue specificity:Widely expressed. Abundant expression seen in the pancreas and testis.,
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Cellular Localization:
Cytoplasm .
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Tissue Expression:
Widely expressed (PubMed:14560022). Abundant expression seen in the pancreas and testis (PubMed:14560022).
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Research Areas:
>>RIG-I-like receptor signaling pathway
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Catalog: YT2978
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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