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Catalog: YN3121
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Collected

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Main Information
Target

VGLU1

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB

MW

60kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of VGLU1 at Human/Mouse/Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
60kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human VGLU1 AA range: 488-538
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Specificity:
This antibody detects endogenous levels of VGLU1 at Human/Mouse/Rat
show all
Gene Name:
SLC17A7 BNPI VGLUT1
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Protein Name:
VGLU1
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Other Name:
Vesicular glutamate transporter 1 ;
VGluT1 ;
Brain-specific Na ;
+ ;
-dependent inorganic phosphate cotransporter ;
Solute carrier family 17 member 7 ;
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Database Link:
Organism Gene ID SwissProt
Human 57030; Q9P2U7;
Mouse 72961; Q3TXX4;
Rat 116638; Q62634;
Background:
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008],
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Function:
Function:Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.,tissue specificity:Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.,
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Cellular Localization:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome .
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Tissue Expression:
Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.
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Research Areas:
>>Synaptic vesicle cycle ;
>>Retrograde endocannabinoid signaling ;
>>Glutamatergic synapse ;
>>Nicotine addiction
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Catalog: YN3121
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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