Catalog: YN3008
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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Main Information
Target
VGLU2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
64kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
VGLU2 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
64kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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RS0002
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
VGLU2 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
SLC17A6 DNPI VGLUT2
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Protein Name:
Vesicular glutamate transporter 2 (VGluT2) (Differentiation-associated BNPI) (Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter) (Solute carrier family 17 member 6)
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Background:
developmental stage:Expressed in fetal brain.,function:Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.,tissue specificity:Predominantly expressed in adult brain. Expressed in amygdala, caudate nucleus, cerebral cortex, frontal lobe, hippocampus, medulla, occipital lobe, puteman, spinal cord, substantia nigra, subthalamic nucleus, temporal lobe and thalamus.,
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Function:
developmental stage:Expressed in fetal brain.,Function:Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.,tissue specificity:Predominantly expressed in adult brain. Expressed in amygdala, caudate nucleus, cerebral cortex, frontal lobe, hippocampus, medulla, occipital lobe, puteman, spinal cord, substantia nigra, subthalamic nucleus, temporal lobe and thalamus.,
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Cellular Localization:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome .
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Tissue Expression:
Predominantly expressed in adult brain (PubMed:10820226). Expressed in amygdala, caudate nucleus, cerebral cortex, frontal lobe, hippocampus, medulla, occipital lobe, putamen, spinal cord, substantia nigra, subthalamic nucleus, temporal lobe and thalamus (PubMed:10820226).
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Research Areas:
>>Synaptic vesicle cycle ;
>>Retrograde endocannabinoid signaling ;
>>Glutamatergic synapse ;
>>Nicotine addiction
>>Retrograde endocannabinoid signaling ;
>>Glutamatergic synapse ;
>>Nicotine addiction
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN3008
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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