Catalog: YN1880
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
PKN3
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
97kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
PKN3 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
97kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
PKN3 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
PKN3 PKNBETA
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Protein Name:
Serine/threonine-protein kinase N3 (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3)
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Background:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,function:Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,
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Function:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Domain:The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,Function:Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,
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Cellular Localization:
Nucleus . Cytoplasm, perinuclear region . Nuclear and perinuclear Golgi region.
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Tissue Expression:
Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.
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Research Areas:
>>PI3K-Akt signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN1880
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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