Catalog: YN1406
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
TSP3
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
105kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
TSP3 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
105kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
TSP3 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
THBS3 TSP3
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Protein Name:
Thrombospondin-3
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Background:
thrombospondin 3(THBS3) Homo sapiens The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011],
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Function:
Function:Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.,similarity:Belongs to the thrombospondin family.,similarity:Contains 1 TSP C-terminal (TSPC) domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 4 EGF-like domains.,similarity:Contains 8 TSP type-3 repeats.,subunit:Oligomer; disulfide-linked.,
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Cellular Localization:
extracellular region,perinuclear region of cytoplasm,
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Tissue Expression:
Lung,PCR rescued clones,Retina,Synovial membrane,
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Research Areas:
>>Phagosome ;
>>PI3K-Akt signaling pathway ;
>>Focal adhesion ;
>>ECM-receptor interaction ;
>>Malaria ;
>>Human papillomavirus infection
>>PI3K-Akt signaling pathway ;
>>Focal adhesion ;
>>ECM-receptor interaction ;
>>Malaria ;
>>Human papillomavirus infection
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Signaling Pathway
Cellular Processes >> Transport and catabolism >> Phagosome
Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> ECM-receptor interaction
Reference Citation({{totalcount}})
Catalog: YN1406
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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