Catalog: YM8166
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
40μL
$190.00
In stock
0
Add to cart
Collected
Collect
Conjugated antibody
Main Information
Target
CD326/EPCAM
Host Species
Rabbit
Reactivity
Human, Mouse, Rat,
Applications
WB, IHC, IF, IP, ELISA
MW
35kD (Calculated)
40kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200,
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
Endogenous
Purification
Protein A
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
35kD
MW(Observed)
40kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PT0290R
Isotype
IgG,Kappa
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Antigen&Target Information
Sequence:
Epithelial cell adhesion molecule
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Specificity:
Endogenous
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Gene Name:
EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1
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Protein Name:
Epithelial cell adhesion molecule
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Other Name:
EPCAM ;
GA733-2 ;
M1S2 ;
M4S1 ;
MIC18 ;
TACSTD1 ;
TROP1 ;
Epithelial cell adhesion molecule ;
Ep-CAM ;
Adenocarcinoma-associated antigen ;
Cell surface glycoprotein Trop-1 ;
Epithelial cell surface antigen ;
Epithelial glycoprotein ;
EGP ;
Epithelial gly
GA733-2 ;
M1S2 ;
M4S1 ;
MIC18 ;
TACSTD1 ;
TROP1 ;
Epithelial cell adhesion molecule ;
Ep-CAM ;
Adenocarcinoma-associated antigen ;
Cell surface glycoprotein Trop-1 ;
Epithelial cell surface antigen ;
Epithelial glycoprotein ;
EGP ;
Epithelial gly
show all
Background:
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008],
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Cellular Localization:
Membrane
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Tissue Expression:
Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.
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Reference Citation({{totalcount}})
Catalog: YM8166
Size
Price
Status
Qty.
200μL
$600.00
In stock
0
100μL
$340.00
In stock
0
40μL
$190.00
In stock
0
Add to cart
Collected
Collect
Conjugated antibody
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