Catalog: KA4325C
Size
Price
Status
Qty.
96well
$330.00
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0
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Main Information
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Human TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit
KE1372
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Antigen&Target Information
Gene Name:
WWOX
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Other Name:
WW domain-containing oxidoreductase ;
Fragile site FRA16D oxidoreductase ;
Fragile site FRA16D oxidoreductase ;
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Function:
skeletal system development, ossification, osteoblast differentiation, induction of apoptosis, steroid metabolic process, negative regulation of signal transduction, negative regulation of cell communication, regulation of cell death,positive regulation of cell death, induction of programmed cell death, regulation of Wnt receptor signaling pathway,negative regulation of Wnt receptor signaling pathway, regulation of apoptosis, positive regulation of apoptosis,regulation of programmed cell death, positive regulation of programmed cell death, skeletal system morphogenesis,oxidation reduction, bone development,
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Cellular Localization:
Cytoplasm . Nucleus . Mitochondrion . Golgi apparatus . Partially localizes to the mitochondria (PubMed:14695174). Translocates to the nucleus upon genotoxic stress or TNF stimulation (By similarity). Translocates to the nucleus in response to TGFB1 (PubMed:19366691). Isoform 5 and isoform 6 may localize in the nucleus. .
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Tissue Expression:
Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be expressed in tumor cell lines.
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Reference Citation({{totalcount}})
Catalog: KA4325C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
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