Catalog: YT7442
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
CLCB
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
25kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of CLCB at Human/Mouse/Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
25kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human CLCB AA range: 168-218
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Specificity:
This antibody detects endogenous levels of CLCB at Human/Mouse/Rat
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Gene Name:
CLTB
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Protein Name:
CLCB
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Database Link:
Background:
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],
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Function:
Function:Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.,subcellular location:Cytoplasmic face of coated pits and vesicles.,subunit:Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R.,
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Cellular Localization:
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic face of coated pits and vesicles.
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Research Areas:
>>Lysosome ;
>>Endocytosis ;
>>Synaptic vesicle cycle ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Huntington disease ;
>>Bacterial invasion of epithelial cells
>>Endocytosis ;
>>Synaptic vesicle cycle ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Huntington disease ;
>>Bacterial invasion of epithelial cells
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT7442
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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