Catalog: YM6918R
Size
Price
Status
Qty.
10mL
$150.00
3 weeks
0
6mL
$120.00
3 weeks
0
3mL
$70.00
3 weeks
0
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Main Information
Target
Vimentin
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
IHC
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
Ready to use for IHC
Formulation
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
Specificity
The antibody can specifically recognize human Vimentin protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year,Ship by ice bag
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT281
Isotype
Mouse IgG1/Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Vimentin AA range: 400-466
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Specificity:
The antibody can specifically recognize human Vimentin protein.
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Gene Name:
VIM
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Protein Name:
Vimentin
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Other Name:
Vimentin
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Database Link:
Background:
This gene encodes a member of the intermediate filament family. Intermediate filamentents , along with microtubules and actin microfilaments , make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape , integrity of the cytoplasm , and stabilizing cytoskeletal interactions. It is also involved in the immune response , and controls the transport of low-density lipoprotein (LDL) -derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment , migration , and cell signaling. Mutations in this gene causes a dominant , pulverulent cataract.[provided by RefSeq , Jun 2009] ,
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Function:
Function:Vimentins are class-III intermediate filaments found in various non-epithelial cells , especially mesenchymal cells. ,online information:Vimentin entry ,PTM:One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division , at which time vimentin filaments are significantly reorganized. ,sequence Caution:Intron retention. ,similarity:Belongs to the intermediate filament family. ,subunit:Homopolymer. Interacts with HCV core protein. Interacts with LGSN and SYNM. ,tissue specificity:Highly expressed in fibroblasts , some expression in T- and B-lymphocytes , and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines. ,
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Cellular Localization:
Cytoplasmic
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Tissue Expression:
Research Areas:
>>Epstein-Barr virus infection ;
>>MicroRNAs in cancer
>>MicroRNAs in cancer
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM6918R
Size
Price
Status
Qty.
10mL
$150.00
3 weeks
0
6mL
$120.00
3 weeks
0
3mL
$70.00
3 weeks
0
Add to cart
Collected
Collect
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