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Galectin 3 (ABT-GAL3) mouse mAb

-YM6764

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Catalog: YM6764
Size
Price
Status
Qty.
200μL
$600.00
In stock

0

100μL
$340.00
In stock

0

40μL
$190.00
In stock

0

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Main Information
Target

Galectin-3

Host Species

Mouse

Reactivity

Human,

Applications

IHC, ELISA

MW

26kD (Calculated)

33kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
IHC 1:50-100; ELISA 1:500-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
The antibody can specifically recognize human Galectin 3 protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
26kD
MW(Observed)
33kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT-GAL3
Isotype
IgG2b,Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Galectin 3 AA range: 150-250
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Specificity:
The antibody can specifically recognize human Galectin 3 protein.
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Gene Name:
LGALS3 MAC2
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Protein Name:
Galectin 3
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Other Name:
Galectin-3 ;
Gal-3 ;
35 kDa lectin ;
Carbohydrate-binding protein 35 ;
CBP 35 ;
Galactose-specific lectin 3 ;
Galactoside-binding protein ;
GALBP ;
IgE-binding protein ;
L-31 ;
Laminin-binding protein ;
Lectin L-29 ;
Mac-2 antigen ;
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Database Link:
Organism Gene ID SwissProt
Human 3958; P17931;
Background:
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014],
Function:
Function:Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.,online information:Galectin-3,similarity:Contains 1 galectin domain.,subcellular location:Cytoplasmic in adenomas and carcinomas. May be secreted by a non-classical secretory pathway and associate with the cell surface.,subunit:Probably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA.,tissue specificity:A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.,
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Cellular Localization:
Cytoplasmic, Nuclear
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Tissue Expression:
A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.
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Catalog: YM6764
Size
Price
Status
Qty.
200μL
$600.00
In stock

0

100μL
$340.00
In stock

0

40μL
$190.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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