Parathyroid Hormone (PTH) (ABT-PTH) mouse mAb (Ready to Use)
-YM6471R
Catalog: YM6471R
Size
Price
Status
Qty.
10mL
$240.00
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6mL
$180.00
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3mL
$120.00
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Main Information
Target
Parathyroid Hormone
Host Species
Mouse
Reactivity
Human,
Applications
IHC
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
Ready to use for IHC
Formulation
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
Specificity
The antibody can specifically recognize human Parathyroid Hormone protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT-PTH
Isotype
IgG1,Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Parathyroid Hormone (PTH) AA range: 50-115
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Specificity:
The antibody can specifically recognize human Parathyroid Hormone protein.
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Gene Name:
PTH
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Protein Name:
Parathyroid hormone (PTH) (Parathormone) (Parathyrin)
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Background:
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Function:
Disease:Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.,Function:PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.,online information:Parathyroid hormone entry,similarity:Belongs to the parathyroid hormone family.,
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Cellular Localization:
Cytoplasmic, Membranous
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Research Areas:
>>Neuroactive ligand-receptor interaction ;
>>Parathyroid hormone synthesis, secretion and action ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Rheumatoid arthritis
>>Parathyroid hormone synthesis, secretion and action ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Rheumatoid arthritis
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Signaling Pathway
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Catalog: YM6471R
Size
Price
Status
Qty.
10mL
$240.00
In stock
0
6mL
$180.00
In stock
0
3mL
$120.00
In stock
0
Add to cart
Collected
Collect
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