Catalog: YM6471R
Size
Price
Status
Qty.
10mL
$150.00
3 weeks
0
6mL
$120.00
3 weeks
0
3mL
$70.00
3 weeks
0
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Main Information
Target
Parathyroid Hormone
Host Species
Mouse
Reactivity
Human
Applications
IHC
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
Ready to use for IHC
Formulation
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
Specificity
The antibody can specifically recognize human Parathyroid Hormone protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year,Ship by ice bag
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT-PTH
Isotype
Mouse IgG1/Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Parathyroid Hormone (PTH) AA range: 50-115
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Specificity:
The antibody can specifically recognize human Parathyroid Hormone protein.
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Gene Name:
PTH
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Protein Name:
Parathyroid hormone (PTH) (Parathormone) (Parathyrin)
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Background:
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein , known as hyperparathyroidism , can result in hypercalcemia and kidney stones. On the other hand , defective processing of the encoded protein may lead to hypoparathyroidism , which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq , Oct 2015] ,
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Function:
Disease:Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. ,Function:PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. ,online information:Parathyroid hormone entry ,similarity:Belongs to the parathyroid hormone family. ,
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Cellular Localization:
Cytoplasmic , Membranous
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Research Areas:
>>Neuroactive ligand-receptor interaction ;
>>Parathyroid hormone synthesis , secretion and action ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Rheumatoid arthritis
>>Parathyroid hormone synthesis , secretion and action ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Rheumatoid arthritis
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM6471R
Size
Price
Status
Qty.
10mL
$150.00
3 weeks
0
6mL
$120.00
3 weeks
0
3mL
$70.00
3 weeks
0
Add to cart
Collected
Collect
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