Catalog: YM6218R
Size
Price
Status
Qty.
10mL
$240.00
In stock
0
6mL
$180.00
In stock
0
3mL
$120.00
In stock
0
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Main Information
Target
Somatostatin
Host Species
Mouse
Reactivity
Human, Mouse, Rat,
Applications
IHC
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
Ready to use for IHC
Formulation
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
Specificity
The antibody can specifically recognize human Somatostatin protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT-SST
Isotype
IgG2b,Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Somatostatin AA range: 50-116
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Specificity:
The antibody can specifically recognize human Somatostatin protein.
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Gene Name:
SST
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Protein Name:
Somatostatin (Growth hormone release-inhibiting factor) [Cleaved into: Somatostatin-28; Somatostatin-14]
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Background:
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008],
Function:
Function:Somatostatin inhibits the release of somatotropin.,online information:Somatostatin entry,pharmaceutical:A synthetic analog known as octreotide or SMS 201-995 is available under the name Sandostatin (Novartis). It is used for the treatment of a variety of disorders including acromegaly and the symptomatic treatment of carcinoid tumors and vasoactive intestinal peptide tumors.,similarity:Belongs to the somatostatin family.,
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Cellular Localization:
Cytoplasmic
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Tissue Expression:
Fetal brain,
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Research Areas:
>>cAMP signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Growth hormone synthesis, secretion and action ;
>>Gastric acid secretion
>>Neuroactive ligand-receptor interaction ;
>>Growth hormone synthesis, secretion and action ;
>>Gastric acid secretion
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Signaling Pathway
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Catalog: YM6218R
Size
Price
Status
Qty.
10mL
$240.00
In stock
0
6mL
$180.00
In stock
0
3mL
$120.00
In stock
0
Add to cart
Collected
Collect
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