Catalog: YM4463
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
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Collected
Collect
Main Information
Target
PLAUR
Host Species
Mouse
Reactivity
Human, Mouse, Rat,
Applications
WB, IF, ELISA
MW
54kD (Calculated)
54kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
This antibody detects endogenous levels of GLUT-1 protein.
Purification
Protein G
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
54kD
MW(Observed)
54kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PTR2138
Isotype
IgG
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Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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RS0002
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Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
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Primary Antibodies
GAPDH (PTR2304) Mouse mAb
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human GLUT-1 AA range: 400-492
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Specificity:
This antibody detects endogenous levels of GLUT-1 protein.
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Gene Name:
SLC2A1 GLUT1
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Protein Name:
Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter)
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Background:
solute carrier family 2 member 1(SLC2A1) Homo sapiens This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013],
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Function:
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake . Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses . Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain . In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity).
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Cellular Localization:
Membranous
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Tissue Expression:
Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.
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Signaling Pathway
Organismal Systems >> Endocrine system >> Insulin secretion
Organismal Systems >> Endocrine system >> Glucagon signaling pathway
Organismal Systems >> Endocrine system >> Adipocytokine signaling pathway
Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: overview >> Central carbon metabolism in cancer
Human Diseases >> Cancer: specific types >> Renal cell carcinoma
Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway
Reference Citation({{totalcount}})
Catalog: YM4463
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
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