Catalog: IHCM6915
Size
Price
Status
Qty.
100mL
$2,960.00
3 weeks
0
10mL
$356.00
3 weeks
0
3mL
$156.00
3 weeks
0
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Collected
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Main Information
Target
TRAP
Host Species
Mouse
Reactivity
Human,
Applications
IHC
Conjugate/Modification
Unmodified
Detailed Information
Specificity
The antibody can specifically recognize human TRAP protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT522
Isotype
IgG1,Kappa
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RS0002
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β-actin (PTR2364) mouse mAb
YM3028
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human TRAP AA range: 250-325
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Specificity:
The antibody can specifically recognize human TRAP protein.
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Gene Name:
ACP5
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Protein Name:
TRAP
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Other Name:
Tartrate-resistant acid phosphatase type 5 ;
TR-AP ;
Tartrate-resistant acid ATPase ;
TrATPase ;
Type 5 acid phosphatase ;
TR-AP ;
Tartrate-resistant acid ATPase ;
TrATPase ;
Type 5 acid phosphatase ;
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Background:
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008],
Function:
Catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,cofactor:Binds 2 iron ions per subunit.,Disease:This relatively minor intracellular isozyme of acid phosphatase can become the dominant isozyme in certain pathological states (Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias).,similarity:Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.,subunit:Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s).,
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Cellular Localization:
Cytoplasmic
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Tissue Expression:
Cytoplasmic
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Research Areas:
>>Riboflavin metabolism ;
>>Metabolic pathways ;
>>Lysosome ;
>>Osteoclast differentiation ;
>>Rheumatoid arthritis
>>Metabolic pathways ;
>>Lysosome ;
>>Osteoclast differentiation ;
>>Rheumatoid arthritis
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: IHCM6915
Size
Price
Status
Qty.
100mL
$2,960.00
3 weeks
0
10mL
$356.00
3 weeks
0
3mL
$156.00
3 weeks
0
Add to cart
Collected
Collect
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