Catalog: IHCM6813
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Price
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Qty.
100mL
$2,960.00
3 weeks
0
10mL
$356.00
3 weeks
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3mL
$156.00
3 weeks
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Main Information
Target
Oct-2
Host Species
Mouse
Reactivity
Human, Mouse,
Applications
IHC
Conjugate/Modification
Unmodified
Detailed Information
Specificity
The antibody can specifically recognize human Oct-2 protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT211
Isotype
IgG2b,Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Oct-2 AA range: 250-350
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Specificity:
The antibody can specifically recognize human Oct-2 protein.
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Gene Name:
POU2F2 OCT2 OTF2
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Protein Name:
Oct-2
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Other Name:
POU domain, class 2, transcription factor 2 ;
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 ;
Octamer-binding protein 2 ;
Oct-2 ;
Octamer-binding transcription factor 2 ;
OTF-2 ;
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 ;
Octamer-binding protein 2 ;
Oct-2 ;
Octamer-binding transcription factor 2 ;
OTF-2 ;
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Background:
The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Function:
Function:Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR and PGR.,tissue specificity:Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line Molt-4, but not in the T-cell line BW 5147.,
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Cellular Localization:
Nuclear
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Tissue Expression:
Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
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Research Areas:
>>Herpes simplex virus 1 infection ;
>>Lipid and atherosclerosis
>>Lipid and atherosclerosis
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Reference Citation({{totalcount}})
Catalog: IHCM6813
Size
Price
Status
Qty.
100mL
$2,960.00
3 weeks
0
10mL
$356.00
3 weeks
0
3mL
$156.00
3 weeks
0
Add to cart
Collected
Collect
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