Catalog: IHCM6765
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Price
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100mL
$2,960.00
1 week
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10mL
$356.00
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3mL
$156.00
1 week
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Main Information
Target
GST-Pi
Host Species
Mouse
Conjugate/Modification
Unmodified
Detailed Information
Specificity
The antibody can specifically recognize human GST-Pi protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year,Ship by ice bag
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT-GSTP1
Isotype
IgG1, Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human GST-Pi AA range: 150-210
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Specificity:
The antibody can specifically recognize human GST-Pi protein.
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Gene Name:
GSTP1 FAEES3 GST3
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Protein Name:
GST-Pi
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Other Name:
Glutathione S-transferase P ;
GST class-pi ;
GSTP1-1 ;
GST class-pi ;
GSTP1-1 ;
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Background:
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical , immunologic , and structural properties , the soluble GSTs are categorized into 4 main classes: alpha , mu , pi , and theta. This GST family member is a polymorphic gene encoding active , functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer , and other diseases. [provided by RefSeq , Jul 2008] ,
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Function:
Catalytic activity:RX + glutathione = HX + R-S-glutathione. ,Function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. ,online information:The Singapore human mutation and polymorphism database ,similarity:Belongs to the GST superfamily. Pi family. ,similarity:Contains 1 GST C-terminal domain. ,similarity:Contains 1 GST N-terminal domain. ,subunit:Homodimer. ,
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Cellular Localization:
Cytoplasmic
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Research Areas:
>>Glutathione metabolism ;
>>Metabolism of xenobiotics by cytochrome P450 ;
>>Drug metabolism - cytochrome P450 ;
>>Drug metabolism - other enzymes ;
>>Metabolic pathways ;
>>Platinum drug resistance ;
>>Pathways in cancer ;
>>Chemical carcinogenesis - DNA adducts ;
>>Prostate cancer ;
>>Hepatocellular carcinoma ;
>>Fluid shear stress and atherosclerosis
>>Metabolism of xenobiotics by cytochrome P450 ;
>>Drug metabolism - cytochrome P450 ;
>>Drug metabolism - other enzymes ;
>>Metabolic pathways ;
>>Platinum drug resistance ;
>>Pathways in cancer ;
>>Chemical carcinogenesis - DNA adducts ;
>>Prostate cancer ;
>>Hepatocellular carcinoma ;
>>Fluid shear stress and atherosclerosis
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: IHCM6765
Size
Price
Status
Qty.
100mL
$2,960.00
1 week
0
10mL
$356.00
1 week
0
3mL
$156.00
1 week
0
Add to cart
Collected
Collect
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