The antibody can specifically recognize human Chromogranin A protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT037
Isotype
IgG1,Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human Chromogranin A AA range: 19-94
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Specificity:
The antibody can specifically recognize human Chromogranin A protein.
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Gene Name:
CHGA
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Protein Name:
beta Granin;betagranin (N-terminal fragment of chromogranin A);catestatin;CgA;CHG A;Chga;chromofungin;Chromogranin A;Chromogranin A parathyroid secretory protein 1;Chromogranin A precursor;ChromograninA;CMGA_HUMAN;ER-37;Pancreastatin;Parastatin;Parathyroid secretory protein 1;Pituitary secretory protein I;Secretory protein I;SP I;SP-I;SP1;SPI;vasostatin 2;Vasostatin;Vasostatin I;Vasostatin II;vasostatin-2
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Other Name:
beta Granin ;
betagranin ;
N-terminal fragment of chromogranin A ;
catestatin ;
CgA ;
CHG A ;
Chga ;
chromofungin ;
Chromogranin A ;
Chromogranin A parathyroid secretory protein 1 ;
Chromogranin A precursor ;
ChromograninA ;
CMGA_HUMAN ;
ER-37 ;
Pancreastatin ;
Parastatin ;
Parathyroid secretory protein 1 ;
Pituitary secretory protein I ;
Secretory protein I ;
SP I ;
SP-I ;
SP1 ;
SPI ;
vasostatin 2 ;
Vasostatin ;
Vasostatin I ;
Vasostatin II ;
vasostatin-2
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014],
Function:
Function:Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.,miscellaneous:Binds calcium with a low-affinity.,PTM:Sulfated on tyrosine residues and/or contains sulfated glycans.,similarity:Belongs to the chromogranin/secretogranin protein family.,subcellular location:Neuroendocrine and endocrine secretory granules.,