Catalog: IHCM6014
Size
Price
Status
Qty.
100mL
$2,960.00
3 weeks
0
10mL
$356.00
3 weeks
0
3mL
$156.00
3 weeks
0
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Collected
Collect
Main Information
Target
CD23
Host Species
Mouse
Reactivity
Human,
Applications
IHC
Conjugate/Modification
Unmodified
Detailed Information
Specificity
The antibody can specifically recognize human CD23 protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year
Modification
Unmodified
Clonality
Monoclonal
Clone Number
ABT-CD23
Isotype
IgG1,Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human CD23 AA range: 200-321
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Specificity:
The antibody can specifically recognize human CD23 protein.
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Gene Name:
FCER2 CD23A CLEC4J FCE2 IGEBF
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Protein Name:
Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleaved into: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form]
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Background:
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],
Function:
Function:This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).,miscellaneous:There are two kinds of Fc receptors for IgE, which differ in both structure and Function: high affinity receptors on basophils and mast cells and low affinity receptors on lymphocytes and monocytes.,online information:CD23,PTM:N- and O-glycosylated.,similarity:Contains 1 C-type lectin domain.,subcellular location:Also exists as a soluble excreted form.,
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Cellular Localization:
Membranous
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Tissue Expression:
B-cell,Blood,
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Research Areas:
>>Hematopoietic cell lineage ;
>>Epstein-Barr virus infection
>>Epstein-Barr virus infection
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Signaling Pathway
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Catalog: IHCM6014
Size
Price
Status
Qty.
100mL
$2,960.00
3 weeks
0
10mL
$356.00
3 weeks
0
3mL
$156.00
3 weeks
0
Add to cart
Collected
Collect
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