Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin. [provided by RefSeq, Jul 2008],
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Function:
Caution:Was originally (PubMed:9367907) thought to be a receptor for adrenomedullin.,Function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.,
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Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Tissue Expression:
Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.