KLF3 rabbit pAb
- Catalog No.:YT7584
- Applications:WB;ELISA;IHC
- Reactivity:Human;Mouse
- Target:
- KLF3
- Fields:
- >>Transcriptional misregulation in cancer
- Gene Name:
- KLF3 BKLF
- Protein Name:
- KLF3
- Human Gene Id:
- 51274
- Human Swiss Prot No:
- P57682
- Mouse Gene Id:
- 16599
- Mouse Swiss Prot No:
- Q60980
- Immunogen:
- Synthesized peptide derived from human KLF3 AA range: 51-101
- Specificity:
- This antibody detects endogenous levels of KLF3 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 38kD
- Function:
- function:Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis.,PTM:Sumoylated by SUMO1. Sumoylation is enhanced by PIAS1, PIAS2alpha and PIAS2beta, and PIAS4, but not by Pc2. Enhances transcriptional repression, but has no effect on DNA binding. Sumoylation on Lys-198 is the major site.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Monomer.,
- Subcellular Location:
- Nucleus .
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).