PAR4 Polyclonal Antibody

    • Catalog No.:YT6160
    • Applications:WB,ELISA
    • Reactivity:Human,Mouse,Rat
    • Description
    • Gene Name:
    • F2RL3 PAR4
    • Protein Name:
    • Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3)
    • Human Gene Id:
    • 9002
    • Human Swiss Prot No:
    • Q96RI0
    • Mouse Swiss Prot No:
    • O88634
    • Immunogen:
    • Synthesized peptide derived from human PAR4 Polyclonal
    • Specificity:
    • This antibody detects endogenous levels of PAR4.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:500-2000, ELISA 1:10000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3)
    • Observed Band(KD):
    • 40
    • Background:
    • F2R like thrombin/trypsin receptor 3(F2RL3) Homo sapiens This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016],
    • Function:
    • function:Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.,PTM:A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets.,
    • Subcellular Location:
    • extracellular region,plasma membrane,integral component of plasma membrane,integral component of membrane,
    • Expression:
    • Lung,Lymphoma,
    • Products Images
    • Western blot analysis of mouse-liver lysate, antibody was diluted at 1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000