PAR4 Polyclonal Antibody

    • Catalog No.:YT6160
    • Applications:WB,ELISA
    • Reactivity:Human,Mouse,Rat
    • Description
    • Gene Name:
    • F2RL3 PAR4
    • Protein Name:
    • Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3)
    • Human Gene Id:
    • 9002
    • Human Swiss Prot No:
    • Q96RI0
    • Mouse Swiss Prot No:
    • O88634
    • Immunogen:
    • Synthesized peptide derived from human PAR4 Polyclonal
    • Specificity:
    • This antibody detects endogenous levels of PAR4.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • WB 1:500-2000, ELISA 1:10000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3)
    • Observed Band(KD):
    • 40
    • Background:
    • F2RL3 encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at F2RL3 may be associated with lung cancer in human patients.
    • Function:
    • cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger,activation of phospholipase C activity, intracellular signaling cascade, blood coagulation, hemostasis, response to wounding, regulation of phospholipase activity, positive regulation of phospholipase activity, positive regulation of phospholipase C activity, second-messenger-mediated signaling, wound healing, positive regulation of catalytic activity, positive regulation of molecular function, phosphoinositide-mediated signaling, coagulation, regulation of body fluid levels, regulation of hydrolase activity, positive regulation of hydrolase activity, regulation of lipase activity,positive regulation of lipase activity,
    • Products Images
    • Western blot analysis of mouse-liver lysate, antibody was diluted at 1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000